Studies on Chloramphenicol. IV

X-ray studies on phospholipid bilayers. XI. Interactions with chloramphenicol.

Chloramphenicol is a widely used antibiotic with low levels of toxicity. However, scanning electron microscopy revealed morphological changes in human erythrocytes when they interacted in vitro with therapeutical concentrations of chloramphenicol. To explain this shape change, a study concerned with the possible interactions of this antibiotic with bilayers built-up of phospholipids located in ...

Biosynthesis of chloramphenicol. IV. Incorporation of carbon 14-labled precursors.

Gottlieb, David (University of Illinois, Urbana), H. E. Carter, P. W. Robbins, and R. W. Burg. Biosynthesis of chloramphenicol. IV. Incorporation of carbon(14)-labeled precursors. J. Bacteriol. 84:888-895. 1962.-Metabolism of dl-phenylalanine stimulated antibiotic synthesis by Streptomyces venezuelae, and resulted in the fixation of carbons 1 and 2 into the carbonyl group of chloramphenicol. It...

Chloramphenicol.

Chloramphenicol (chloromycetin), an Antibiotic. Pharmacological and Pathological Studies in Animals.

It is a neutral white crystalline substance with a bitter taste and is stable in neutral and acid solutions. The drug is moderately soluble in water (0.25 per cent at room temperature, 0.65 per cent at 700 C and up to 15 per cent in propylene glycol, 5 per cent in 50 per cent acetamide), and is insoluble in vegetable oils. Solubility in urine or serum is about the same as in water. Solutions ar...

Studies on Self-Sterility. IV. Selective Fertilization.

INTRODUCTION .................................................................. 346 Discussion of the problem ..................................................... 348 Pollen-tube frequency distributions ............................................. 349 Influence of growth of compatible pollen tubes upon incompatible pollen tubes.. .. 352 SUMMARY AND DISCUSSION ....................................